- Use a skin lubricant in more commonly chaffed areas prior to running - it can act as a barrier between skin and clothes and also skin-on-skin. Common lubricants include BodyGlide, SportShield, Vaseline, Squeaky Cheeks, and Aquaphor.
- Wear closer-fitting running apparel to reduce the amount of friction between excess fabric and your skin. If you're experiencing more skin-on-skin contact, using compression garments might help eliminate this.
- Some people are irritated by the friction of cotton tee-shirts and choose to wear more synthetic materials. These fabrics are also designed to wick away moisture, which will help prevent chaffing as well.
- Wear proper sizes with your socks and shoes (blisters count as chaffing!), and also with your sports bra. There shouldn't be excess friction between your bra and your skin. Finding the proper sports bra size will reduce or eliminate the risk of chaffing.
- Stay hydrated throughout your run so your body can work better at cooling itself.
If you're done with your run and are experiencing the "chub rub," make sure to dry the area well. If the skin is not broken, you can apply a cream with a combination of vitamins A and D in it. If the rash persists or the skin is broken, seek medical treatment as these are indications it might be infected.